These tools often paired with

LangChainvsAutoGen

The leading LLM app framework versus Conversational multi-agent framework — superseded by Microsoft Agent Framework

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Choose LangChain when…

  • You want a broad, flexible LLM orchestration toolkit
  • You need integrations with many tools and data sources
  • You're prototyping or exploring LLM app patterns

Choose AutoGen when…

  • You want conversational multi-agent orchestration
  • Research or Microsoft ecosystem integration matters
  • You need flexible human-in-the-loop patterns

Side-by-side comparison

Field
LangChain
AutoGen
Category
Pipelines & RAG
Agent Frameworks
Type
Open Source
Open Source
Free Tier
✓ Yes
✓ Yes
Pricing Plans
GitHub Stars
93,000
34,000
Health
100 Active
70 Active

LangChain

Most widely used framework for building LLM applications. Chains, agents, RAG pipelines, and deep integrations with 300+ tools.

AutoGen

Microsoft research framework for building multi-agent systems through conversational patterns. Officially superseded by Microsoft Agent Framework 1.0 (April 2026), which merges AutoGen and Semantic Kernel. Large installed base remains; Microsoft publishes a migration path.

Shared Connections5 tools both integrate with

Only LangChain (28)

OpenHandsAutoGenSemantic KernelLangSmithLlamaIndexQdrantChromaPineconeWeaviatepgvector

Only AutoGen (2)

LangChainMicrosoft Agent Framework

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See how LangChain and AutoGen fit into the bigger picture — 235 tools, 543 relationships, all mapped.

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