These tools integrates with

LettavsOpenAI API

Stateful agents with long-term memory — formerly MemGPT versus GPT-5 era models, embeddings, and Responses API from OpenAI

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Choose Letta when…

  • need agents with persistent cross-session memory
  • context window length is limiting your application
  • building personal assistants or long-running agents

Choose OpenAI API when…

  • You need the broadest ecosystem and most integrations
  • GPT-4 or o-series reasoning models are required
  • Assistants API, fine-tuning, or batch API are needed

Side-by-side comparison

Field
Letta
OpenAI API
Category
Agent Frameworks
LLM Infrastructure
Type
Open Source
Commercial
Free Tier
✓ Yes
✗ No
Pricing Plans
Open Source: FreeCloud: $20/mo
API: Per token
GitHub Stars
13,200
Health
100 Active

Letta

Letta (formerly MemGPT) is an open-source framework for building stateful AI agents with persistent, editable memory. Agents remember conversations across sessions, search their own memory, and update their knowledge over time — solving context window limitations.

OpenAI API

API access to GPT-5, GPT-5.5, o3/o4 reasoning models, and the Responses API; plus embeddings, image, audio, and Realtime endpoints. The most widely deployed LLM API in production.

Only Letta (2)

LangGraphOpenAI API

Only OpenAI API (39)

CrewAIAutoGenLlamaIndexLangChainPydanticAIsmolagentsAgnoMastraLiteLLMPortKey

Explore the full AI landscape

See how Letta and OpenAI API fit into the bigger picture — 235 tools, 543 relationships, all mapped.

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